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Causes of ONJ / At Risk Medications
Causes of osteonecrosis of the jaw include cancer, radiation therapy, chemotherapy, chemotherapy using nitrogenous bisphosphonates and osteoporosis oral bisphosphonates.
The table below lists all oral and i.v. bisphosphonates currently on the market in the U.S. which may cause Osteonecrosis of the Jaw.
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Orally Administered Bisphosphonates
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| Brand Name |
Manufacturer |
Generic Name |
| Actonel |
Procter & Gamble Pharmaceuticals |
risedronate |
| Boniva |
Roche Laboratories |
ibandronate |
| Fosamax |
Merck & Co. |
alendronate |
| Fosamax Plus D |
Merck & Co. |
alendronate |
| Skelid |
Sanofi Pharmaceuticals |
tiludronate |
| Didronel |
Procter & Gamble Pharmaceuticals |
etidronate |
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Intravenously Administered Bisphosphonates
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| Brand Name |
Manufacturer |
Generic Name |
| Aredia |
Novartis |
pamidronate |
| Zometa |
Novartis |
zolendronic acid |
| Bonefos |
Schering AG |
clodronate |
Find out more about
Fosamax and Osteonecrosis of the Jaw
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